The CEPH consortium linkage map of human chromosome 16.

Abstract : A Centre d'Etude du Polymorphisme Humain (CEPH) consortium map of human chromosome 16 has been constructed. The map contains 158 loci defined by 191 different probe/restriction enzyme combinations or primer pairs. The marker genotypes, contributed by 9 collaborating laboratories, originated from the CEPH families DNA. A total of 60 loci, with an average heterozygosity of 68%, have been placed on the framework genetic map. The genetic map contains 7 genes. The length of the sex-averaged map is 165 cM, with a mean genetic distance between loci of 2.8 cM; the median distance between markers is 2.0 cM. The male map length is 136 cM, and the female map length is 197 cM. The map covers virtually the entire chromosome, from D16S85, within 170 to 430 kb of the 16p telomere, to D16S303 at 16qter. The markers included in the linkage map have been physically mapped on a partial human chromosome 16 somatic cell hybrid panel, thus anchoring the genetic map to the cytogenetic-based physical map.
Type de document :
Article dans une revue
Genomics, Elsevier, 1995, 25 (1), pp.44-58
Liste complète des métadonnées

https://hal-ensta.archives-ouvertes.fr/hal-01160658
Contributeur : Gilles Vergnaud <>
Soumis le : samedi 6 juin 2015 - 16:53:03
Dernière modification le : jeudi 1 février 2018 - 01:32:00

Identifiants

  • HAL Id : hal-01160658, version 1
  • PUBMED : 7774955

Collections

Citation

H M Kozman, T P Keith, H Donis-Keller, R L White, J Weissenbach, et al.. The CEPH consortium linkage map of human chromosome 16.. Genomics, Elsevier, 1995, 25 (1), pp.44-58. 〈hal-01160658〉

Partager

Métriques

Consultations de la notice

138