Spectral and spatial shaping of a laser-produced ion beam for radiation-biology experiments

Abstract : The study of radiation biology on laser-based accelerators is most interesting due to the unique irradiation conditions they can produce, in terms of peak current and duration of the irradiation. In this paper we present the implementation of a beam transport system to transport and shape the proton beam generated by laser-target interaction for in vitro irradiation of biological samples. A set of four permanent magnet quadrupoles is used to transport and focus the beam, efficiently shaping the spectrum and providing a large and relatively uniform irradiation surface. Real time, absolutely calibrated, dosimetry is installed on the beam line, to enable shot-to-shot control of dose deposition in the irradiated volume. Preliminary results of cell sample irradiation are presented to validate the robustness of the full system.
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Physical Review Accelerators and Beams, 2017, 20 (3), 〈10.1103/PhysRevAccelBeams.20.032801〉
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https://hal-ensta.archives-ouvertes.fr/hal-01515426
Contributeur : Pierre Zaparucha <>
Soumis le : jeudi 27 avril 2017 - 14:46:16
Dernière modification le : jeudi 10 mai 2018 - 01:58:17

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L. Pommarel, B. Vauzour, F. Mégnin-Chanet, E. Bayart, O. Delmas, et al.. Spectral and spatial shaping of a laser-produced ion beam for radiation-biology experiments. Physical Review Accelerators and Beams, 2017, 20 (3), 〈10.1103/PhysRevAccelBeams.20.032801〉. 〈hal-01515426〉

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